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The Ultimate Guide to Pharmaceutical Packaging: Types, Materials & Machinery

Jun 20, 2025

Pharmaceutical packaging plays a vital role in medicine protection, maintaining drug efficacy and guaranteeing patient safety. Whether you're a pharmaceutical manufacturer, supplement company, or packaging supplier, in this guide you will learn the main types of pharmaceutical packaging, materials used, machinery involved, and trends shaping the future of pharma packaging.

 

 

 

1. What Is Pharmaceutical Packaging?

Pharmaceutical packaging refers to the process of enclosing pharmaceutical products, such as tablets, capsules, liquids, powders, or injectables, in containers that ensure their safety, stability, and usability from production to final consumption. Pharma packaging includes a wide range of packaging types, materials, and technologies designed for multiple purposes.

 

Key Functions of Pharmaceutical Packaging:

• Protection: Shields the product from physical damage, microbial contamination, UV light, moisture, and oxygen.

• Preservation: Helps maintain the chemical and physical stability of the medication while in storage or during transport.

• Identification: Displays crucial details such as the drug name, dosage, batch number, expiry date, and manufacturer, etc.

 Patient Safety & Compliance: Ensures ease of use, accurate dosing, and tamper-evident features to prevent misuse.

• Regulatory Compliance: Meets GMP, serialization, and labeling requirements for global distribution.

 

2. Main Categories of Pharmaceutical Packaging

Pharmaceutical packaging can be divided into three main categories: primary, secondary, and tertiary packaging, each packaging technology serving a unique purpose in the pharmaceutical supply chain.

 

1) Primary Packaging of Pharma Packing

 

Primary packaging is the first layer of medicine packaging that directly contact with the products such as pills, tablets, capsules, etc. It is essential for preserving drug stability and avoiding contamination. This type of pharma packing must meet strict GMP (Good Manufacturing Practice) and FDA/EMA guidelines.

 

 

 

Common examples of primary pharmaceutical packaging include:

• Blister packs for tablets and capsules.

• Plastic or glass bottles for liquid syrups or solid doses.

• Vials and ampoules for injectables.

• Sachets and pouches for powders and single-use doses.

 

2) Secondary Packaging of Pharma Packing

Secondary packaging for pharma industry is the outer layer that holds one or more primary packages. It is vital for branding, labeling, patient information, and tamper evidence. Though it doesn't touch the product directly, it's essential for regulatory compliance and consumer trust.

 

 

Typical secondary pharma packaging formats include:

• Flow wrappings

• Cardboard cartons

• Printed boxes with product inserts

• Shrink-wrapped bundles

 

Secondary packaging often includes important information like dosage instructions, lot numbers, and expiration dates, supporting pharmaceutical traceability and patient safety.

 

3) Tertiary Packaging of Pharma Packing

 

Tertiary packaging is made for bulk handling, shipping, and logistics. It ensures that pharmaceutical products reach hospitals, pharmacies, and distributors intact and undamaged during transportation.

 

 

 

Examples of tertiary pharmaceutical packaging:

• Corrugated shipping cartons

• Wooden or plastic pallets

• Bulk containers and crates

 

This packaging layer is especially important for cold chain logistics especially for temperature-sensitive medications such as vaccines and biologics.

 

 

3. Top 5 Popular Types of Pharmaceutical Packaging

 

Pharmaceutical packaging is widely used in the industry, but do you know what are the top 5 most popular types of pharmaceutical packaging?

 

1) Blister Packs (for Tablets and Capsules)

Blister packs are among the most commonly used primary packaging solutions in the pharmaceutical industry. They are made of a pre-formed plastic cavity that is sealed with an aluminum or plastic foil backing. Each pocket contains a single dose, helping to protect against humidity and oxidation, enhance patient compliance with unit-dose packaging and reduce the risk of contamination during handling.

 

 

Here is a brief table for the general information of blister packaging.

Feature

Description

Advantages

- Unit-dose control

- High barrier protection

- Tamper-evident

Applications

- Tablets Pills

- Capsules Pills

- Nutritional supplements

Materials Used

- PVC/Alu- Alu/Alu (cold form)- PVDC laminated films

Machines Used

- Blister Packing Machine

- Thermoforming Machine

Regulatory Fit

GMP, FDA, EU pharmaceutical packaging standards

 

2) Plastic or Glass Bottles (for Liquids and Solids)

Bottles are versatile containers used for oral liquids, syrups, vitamins, and solid doses like capsules and tablets. There are major two types of bottles which are:

• Plastic bottles (usually HDPE or PET) are lightweight, shatter-resistant, and cost-effective.

• Glass bottles (often amber or clear) provide superior chemical resistance and are ideal for light-sensitive medications.

 

 

Here is a brief table for the general information of bottle packaging.

Feature

Description

Advantages

- Ideal for bulk packaging

- Reclosable, tamper-evident

- Easy dispensing

Applications

- Capsules, tablets, softgels

- Gummies and powders

- Syrups

- Oral liquids

Materials Used

- PET, HDPE plastic bottles

- Glass bottles

Machines Used

- Tablet Counting Machine

- Capping Machine

- Induction Sealer

- Labeling Machine

- Liquid filling machine (for oral liquids and syrups,etc)

Regulatory Fit

cGMP, FDA, HACCP compliant for nutraceuticals and pharma

 

3) Sachets and Stick Packs (for Powders and Single-Use Doses)

Sachets and stick packs are flexible packaging formats made from laminated films that provide barrier protection against moisture, oxygen, and UV light. They are popular in both pharmaceuticals and nutraceuticals for the reason of convenience, portability, and accurate dosing.

 

 

 

Here is a table for the overall information for the sachet and stick pack packaging.

Feature

Description

Advantages

- Lightweight, portable, single-serve

- Excellent barrier protection

- Customizable shapes (3-side seal, 4-side seal, stick)

- Cost-effective for mass production

- Ideal for precise dosage

Applications

- Nutraceutical powders (collagen, probiotics)

- Electrolyte drinks (ORS)

- Instant coffee & tea

- Enzymes, herbal supplements

- Creams, gels, honey, and syrups

Materials Used

- PET/AL/PE multilayer laminates

- Paper/poly/foil

- Heat-sealable films

Machines Used

- Vertical Form Fill Seal (VFFS) Machine

- Stick Pack Machine

- Sachet Packing Machine (3-side/4-side seal)

- Multilane Packing Machine

- Auger or volumetric dosing systems

Regulatory Fit

- cGMP, HACCP, FDA, ISO22000 (especially for food & pharma)- Supports serialized coding and tamper-evidence

Common Variants

- 3-side seal sachets

- 4-side seal sachets

- Back seal sachets

- Center-seal sticks

- Twin-stick or dual chamber packs

 

4) Strip Packaging for Tablets and Capsules

Strip packaging is a type of unit-dose packaging where tablets or capsules are individually sealed between layers of flexible film, typically aluminum or plastic laminate. It offers excellent moisture, light, and air protection, making it ideal for sensitive or pediatric medications.

 

 

 

 

Here is the information for the strip packing packaging in terms of advantages, applications, etc.

Feature

Details

Advantages

- Airtight, tamper-proof

- Compact size

- Longer shelf life

Applications

Tablets, lozenges, chewables

Materials Used

- Aluminum foil

- Paper-aluminum-poly film

- PE/Alu composite

Machines Used

Strip Packing Machine

Key Insights

Often used for moisture-sensitive or pediatric formulations

 

5) Vials and Ampoules (for Injectables)

Used primarily for injectable drugs, vaccines, and biological products, vials and ampoules are critical for sterile pharmaceutical packaging.

• Vials are small cylindrical containers with a rubber stopper and aluminum seal. Available in both single-dose and multi-dose formats, ideal for reconstitution.

• Ampoules are sealed glass containers designed to be opened by breaking. They offer extraordinary protection against contamination and air exposure.

 

 

 

Here is a table for the overall information of vials and ampoules.

Feature

Details

Advantages

- Ideal for injectables

- High sterility and barrier

- Tamper-proof

Applications

Vaccines, insulin, antibiotics, eye drops

Materials Used

Type I glass, plastic (COP/COC), rubber stoppers, aluminum crimp caps

Machines Used

- Vial Filling Line (Filler + Stopper + Crimper)

- Ampoule Filling & Sealing Machine

Key Insights

Vials use stopper + crimp; Ampoules are flame-sealed glass tubes

 

4. How to Choose the Right Pharmaceutical Packaging?

Choosing the right pharmaceutical packaging is essential for maintaining pill’s stability, meeting regulatory compliance, and guaranteeing patient safety. With so many formats such as blisters, bottles, vials, sachets, it's important to match your product with the right packaging based on its form, sensitivity, target market, and production needs.

 

The table below helps simplify this decision by comparing key factors like applications, advantages, and compatible machinery.

Criteria

Details

Examples / Packaging Types

1. Dosage Form

Match packaging to the physical form of the product.

- Tablets: Blister, Bottle, Strip

- Liquids: Bottle, Vial, Ampoule

- Powders: Sachet, Stick Pack

2. Product Sensitivity

Consider protection from moisture, light, and oxygen.

- Moisture-sensitive: Alu-Alu Blister, Strip Packing

- Light-sensitive: Amber Bottle, Foil Pouch

3. Patient Compliance

Ensure packaging is easy to open, dose, and store, especially for elderly or children.

- Easy-open bottles

- Unit-dose blister/strip- Calendar packs for daily use

4. Regulatory Compliance

Packaging must meet country-specific regulations (e.g., FDA, EMA, GMP), and often include tamper evidence and serialization.

- Child-resistant caps

- Tamper-evident seals

- Serialized labels

5. Target Market

Consider the packaging's appearance, portability, and ease of distribution, especially in retail or export scenarios.

- Schet & Stick pack for on-the-go users

- Bottles for retail shelves

- Blister packing for hospitals

6. Shelf Life Requirements

Choose high-barrier materials for longer shelf life or unstable APIs.

- Alu-Alu blister packaging

- Multi-layer films for sachets

- Glass vials with rubber stoppers

7. Production Scale

Match packaging format to your production volume and line efficiency.

- Blister: medium-high speed

- Bottles: bulk and fast filling

- Sachets: efficient for powders

8. Cost Considerations

Balance between material cost, machine investment, and per-unit packaging expense.

- Bottles: higher material cost, low labor

- Stick packs: low material cost per unit

 

Packaging Type & Machine Compatibility Overview

Packaging Type

Machines Required

Blister Packaging

Blister Packing Machine (Alu-PVC, Alu-Alu, Paper-PVC)

Tablet Bottle Packaging

Bottle Unscrambler, Tablet Counting Machine, Capping Machine, Induction Sealing Machine, Labeling Machine 

Sachet/Stick Packaging

Vertical Form Fill Seal Machine (Multilane)

Strip Packaging

Strip Packing Machine

Vial/Ampoule Packaging

Liquid Filling Machine, Stoppering or Flame Sealing Machine, Sterilizer, Cap Crimper

 

 

5. Top Pharmaceutical Packaging Suppliers & Manufacturers

Choosing a reliable pharmaceutical packaging supplier is very important for multiple reasons. Whether you’re sourcing primary packaging materials (like blisters, bottles, or vials) or looking for end-to-end pharmaceutical packaging solutions, these trusted companies offer proven expertise in the pharmaceutical industry.

 

Supplier/

Manufacturer

Country

Specialties

Why Choose Them

Schott AG

Germany

Glass vials, ampoules, cartridges, syringes

Industry leader in high-purity pharmaceutical glass and injectable packaging.

Gerresheimer

Germany

Glass & plastic packaging, vials, prefillable syringes

Strong global presence and expertise in biologics packaging.

West Pharmaceutical

USA

Rubber stoppers, seals, injectable component systems

Trusted for injectable packaging components and container-closure integrity.

Rich Packing Machinery

China

Blister packing machines, capsule filling, tablet counters, tablet capsule counting bottling line.

One-stop solution for automated pharmaceutical packaging machines, with local service available.

Ruidapacking

China

Blister packaging,

Tablet counting machine, Sachet packaging machines, etc.

Specialized in custom packaging lines for supplements and pharma, with global on-site support.

Jinlupacking

China

Blister machines, softgel packaging, tablet capsule counting and filling line.

Cost-effective machinery with global support for small and large-scale manufacturers.

Origin Pharma

UK

Primary packaging materials, design & sourcing solutions

Ideal for startups and formulation developers needing agile packaging support.

 

6Frequently Asked Questions (FAQ) About Pharmaceutical Packaging

Q1: What is the most commonly used packaging in the pharmaceutical industry?

Blister packaging is one of the most widely used formats due to its excellent protection, ease of use, and individual unit dosing. It's especially popular for tablets and capsules.

 

Q2. What’s the difference between primary and secondary pharmaceutical packaging?

• Primary packaging directly touches the drug (e.g., blister, bottle, vial).

• Secondary packaging is the external layer that holds and protects the primary package (e.g., cartons, boxes).

 

Q3. Which packaging is best for moisture-sensitive medicines?

Blister packaging and amber glass bottles are ideal for moisture-sensitive products, offering superior barrier protection.

 

Q4. Are sachets and stick packs suitable for pharmaceuticals?

Yes, both formats are widely used for powders, granules, and oral rehydration salts. They are convenient, portable, and ideal for single doses.

 

Q5. Can one machine handle multiple types of pharmaceutical packaging?

Generally, no. Packaging machines are designed for specific formats (e.g., blister, bottle, sachet). However, modular or multi-functional systems can sometimes be adapted with different change parts.

 

Q6. What certifications should I look for in a pharmaceutical packaging supplier?

Key certifications include GMP, ISO, SA8000, CE, the choice rely on your target market and type of products.

 

7. Conclusion

Pharmaceutical packaging is essential for ensuring drug safety, stability, and compliance throughout the product lifecycle. From blisters and bottles to sachets, strips, vials, and ampoules, each packaging type serves a unique purpose based on product form, sensitivity, and market needs. By understanding the materials, machinery, and regulatory requirements involved, manufacturers can choose the most efficient and effective packaging solutions. 

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